Stretching single talin rod molecules activates vinculin binding. in vitro, only the sequence from abp140 reduced binding of PA to a cross receptor. The actin binding regions of ANTXR1 and abp140, but not the WH2 domain name, colocalized with actin stress fibres, which suggested that filamentous actin regulates ANTXR1. Consistent with this notion, disruption of … Continue reading Stretching single talin rod molecules activates vinculin binding